Chagas Disease

The serological antibody repertoire in Chagas Disease

Towards a comprehensive description of the specificities of individual antibody repertoires in Chagas Disease

Target-based screening of the Chagas box: setting up enzymatic assays to discover specific inhibitors across bioactive compounds.

Chagas disease is a neglected tropical illness caused by the protozoan parasite Trypanosoma cruzi. The disease is endemic in Latin America with about 6 million people infected and many more being at risk. Only two drugs are available for treatment, …

Discovery and fine epitope mapping of novel serology-based markers for diagnosis of Congenital Chagas Disease using high-density peptide chips

How we use this technology to discover new antigens and epitopes in matched mother-newborn samples

Next-generation ELISA diagnostic assay for Chagas Disease based on the combination of short peptidic epitopes

Chagas disease, caused by the parasite Trypanosoma cruzi, is a life-long and debilitating illness of major significance throughout Latin America, and an emergent threat to global public health. Diagnostic tests are key tools to support disease …

Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps

Immunomics of Infectious Diseases

High-throuput screening and data integration for diagnostics tool development

Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants

Setting the stage for high-throughput immunomics in Chagas Disease

Diagnostic peptide discovery: prioritization of pathogen diagnostic markers using multiple features