Working on data integration to discover new drugs and diagnostics for human pathogens.
Our laboratory is interested in the study of human pathogens, particularly trypanosomes and also others that cause so-called Neglected Tropical Diseases.
We develop computational tools and produce (and re-use) large data sets to formulate and guide our research hypotheses in the quest for new drugs and diagnostics. Smart and intensive data integration, data mining, and high-throughput assays and experiments are at the core of our research activities.
In particular, we have a special interest in the study of trypanosomes such as Trypanosoma cruzi (causative of Chagas disease).
Wellcome to our electronic home in the web. Feel free to browse and poke around.
A chemogenomics resource for neglected diseases
A tool for genome-wide antigenicity predictions
An Atlas of Chagas Disease Antigens and Epitopes
Identification and repurposing of bioactive compounds for Chagas disease: combining chemogenomics with high-throughput phenotypic screening
A map of genetic variation for Trypanosoma cruzi and its use on strain typing applications
Antigens discovery for congenital Chagas disease, mapping and validation of epitopes for newborns serological diagnosis kit.
High-throuput screening and data integration for diagnostics tool development
The people behind the tryps
Diagnostics, Drug Discovery, Bioinformatics, Genomics, Neglected Diseases, Trypanosomes
Chemogenomics, Biochemistry, High-Throughput Screenings
Chagas Disease, Bioinformatics, Neural Networks
Diagnostics, Bioinformatics, Neglected Diseases, Congenital Chagas, Trypanosomes
Chemogenomics, Neglected diseases, Drug Discovery
Chemogenomics, Neglected Diseases, Drug Discovery